Mission 1: Hidden Red Orbs
Go to the part at the beginning where you double jump over the rubble blocking the way ahead. Face the statue and double jump to the statue's shoulder, then again to his head. Once on his head, at many Red Orbs will fall.

Mission 1: Unlimited Red Orbs
Get the first Red Orb at the beginning then keep restarting the mission.

Mission 1: Unlimited Yellow Orbs
After completing either character's game at least once and have unlocked the "Mission Select" option, go to mission 1 and collect the Yellow Orbs. Save the game and quit. You may now continue where you left off. This trick is useful when facing the tougher Bosses on the harder settings.

Mission 2: Hidden areas
Enter one of the rooms that has a coffin and bones in it. Go up to the coffin and press Circle. This will take you to a hidden room full of enemies and some Red Orbs. There are actually two secret areas in mission 2. Both are in separate rooms where skeleton coffins are located. Check every coffin you see to find them.

Mission 3: Hidden area
Before or after the cargo elevator trip, you will reach a door located between two other doors with just a couple of stair steps. Stand in front of the door on the left side of the screen and press Circle to enter a secret room.

Mission 4: Hidden area
When you start, look for the first door on your left. It is not very big and is sticking out slightly. Approach it and press Circle. It will lead to a secret area where big flying creatures attack you.

Mission 5: Hidden area
When you enter the barricaded area, go to Dante's left and fall off the cliff. There are several medium Red Orbs. Follow that until the end. There will be an Orb Dispenser. Go just to the left of the Orb Dispenser to find a garage-type door. Press Circle, and there will be plenty of Homromsira in there.

Mission 6: Defeating the "head"
When you are fighting the "head", not when it is the full body, when it falls on the ground and starts shooting lasers, wait for them to stop. You will have a few seconds before it will go into the air again. In that time, run up to it and hit it with your sword on the open mouth. It will do double or triple the damage. When the head floats down to the ground and shoots its lasers, press Circle to flip Dante around to the back of the head. Slash the monster while it is shooting the
lasers. After it is done, using the sword will help Dante's Devil Trigger to fill up. When it is full, it will do even more damage.

Mission 7: Hidden area
At the very end of the mission, before entering the door that leads to the roof, press Circle at the door to the left.

Mission 8: Easy Red Orbs
The level select option must first be unlocked for this trick .Select level 8. Fight and defeat the opponent as quickly as possible without using items. You will get about 4,000 Red Orbs if you get a "B" rank.

Mission 10: Hidden area
After defeating the giant butterfly and the larvae, you will go down a set of stairs. After the game loads, go to the first set of doors you see and press Circle to enter another hidden room.

Mission 14: Hidden area
When you start the mission, turn around and press Circle against the door on the left. You should enter a secret room with enemies to fight.

Mission 16: Hidden area
On this mission, you will enter a room where you will find the item named Sacrilege. Get the item to make the energy balls stop coming at you. Then, on the floor directly under the balcony where the item was located, there will be a wall that resembles a door. Press Circle in front of that wall and it will open a secret room.

Mission 16: Easy Red Orbs
When you pass mission 16, you can get as many red orbs as desired. Go up and down the elevator, killing all enemies. Remember to mix up your attacks to increase your stylish bonus. Do not use a maxed-out weapon, as this will kill enemies too quickly and not allow you to get your stylish up fast enough. If done correctly, you can get up to 2,500 Red Orbs on each trip up and down the elevator. This may get tedious, but is well worth it when you get to the "Must Die" modes. Save your data when you have the desired number of orbs.

Defeating Possessed Arius
Note: You can only fight Possessed Arius as Lucia. When you get to the second to last mission (after the part where you are in the Big Urobos Buildiing Corps.), you will have to fight Possessed Arius. He is also in Devil Trigger Mode. To defeat him, find the Embaka and have it upgraded to at least level 2 or 3. Have your Arsenal, Throwing Daggers, upgraded to level 2. While fighting, keep jumping in the air and pressing Square rapidly until you fall. At least every five to ten seconds, Possessed Arius will charge up (purple flames will form around his body). He will charge at you. Jump in the air and keep pressing Square. When he is behind you while you a're in the air, he might jump at you on the ground. When he falls, attack him with Triangle. It is the best way to get your Devil Trigger gauge at full power. If your Devil Trigger gauge is half to full, go into Devil Trigger mode. Keep attacking him; you will rarely ever fall down while you attack in Devil Trigger mode. When his life is in the red, he will take one of the pipe-like things on his back that always move and jam it into the ground, causing it to pop up occasionally, He will not die, but will transform another time.

You do not need to have anything leveled up for this trick, but you will need the Speed Amulet. Equip the Throwing Daggers. When you start out in the pit, run as far from him as possible. Throw daggers at him until he is almost close enough to hit you, then Devil Trigger and run under him to the other side of the pit. Repeat this strategy. Note: Your Devil Trigger should charge up just enough. If you defeat the second form quickly and you do this trick on the third form correctly, you should be able to get an "S" rank for time, and high ranking for damage, although style will probably get a "D" rank.

Defeating the Infested Tanks
Have Lucia jump on to the tank. Note: Make sure you have your handguns on. Jump once then fire. Before you land, jump again and fire. When you defeat the first one, do it again. Note: Watch your back, as the other ones might fire a missle. There are three of them.